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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.160nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.190nMAssay Description:The compound was tested for inhibition of rhesus monkey plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  3.70nMAssay Description:Binding affinity of the compound was determined against Nicotinic acetylcholine receptor using [3H]-(-)-nicotine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  21nMpH: 7.4Assay Description:The compound was tested for inhibition of rat plasma renin at pH of 7.4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  27nMAssay Description:The compound was tested for inhibition of rabbit liver cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  28nMAssay Description:The compound was tested for inhibition of porcine pepsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rhizopus chinensis)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  230nMpH: 7.4Assay Description:Inhibition of rhizopuspepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rhizopus chinensis)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  230nMAssay Description:Binding affinity against nicotinic acetylcholine receptor alpha4-beta4 using [3H]epibatidine as radioligand expressed in HEK293 cells or tsA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  1.20E+4nMAssay Description:The compound was tested for inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed