Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50025073(CHEMBL2372187)Copy SMILESCopy InChI

Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein ADM2(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50025073(CHEMBL2372187)Copy SMILESCopy InChI

Affinity DataIC50:  496nMAssay Description:Antagonist activity at human adrenomedullin 2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI