Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human SRC using poly(Glu,Tyr)4:1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of recombinant human IGF1-R using poly(Glu,Tyr)4:1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of recombinant human VEGF-R2 using poly(Glu,Tyr)4:1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  9.33E+3nMAssay Description:Inhibition of recombinant human ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of recombinant human FAK using poly(Glu,Tyr)4:1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of recombinant human AXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of wild type human MET using poly(Ala,Glu,Lys,Tyr) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50:  3.81E+4nMAssay Description:Inhibition of recombinant human Aurora-B using tetra(LRRWLSG) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human PRK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human PLK1 using casein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human PIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human NEK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human NEK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type human MEK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50358243(CHEMBL1922224)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human AKT1 using GSK3 (amino acids 14 to 27) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed