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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of recombinant human SRC using poly(Glu,Tyr)4:1 as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 3.16E+3nM
Assay Description:
Inhibition of recombinant human IGF1-R using poly(Glu,Tyr)4:1 as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 4.95E+3nM
Assay Description:
Inhibition of recombinant human VEGF-R2 using poly(Glu,Tyr)4:1 as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 9.33E+3nM
Assay Description:
Inhibition of recombinant human ALK
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
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Article
PubMed
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Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 1.69E+4nM
Assay Description:
Inhibition of recombinant human FAK using poly(Glu,Tyr)4:1 as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 2.19E+4nM
Assay Description:
Inhibition of recombinant human AXL
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 3.40E+4nM
Assay Description:
Inhibition of wild type human MET using poly(Ala,Glu,Lys,Tyr) as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Aurora kinase B
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: 3.81E+4nM
Assay Description:
Inhibition of recombinant human Aurora-B using tetra(LRRWLSG) as substrate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human PRK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human PLK1 using casein as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human PIM1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase Nek6
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human NEK6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human NEK2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of wild type human MEK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human ARK5
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Peking University
Curated by
ChEMBL
Ligand
BDBM50358243
(CHEMBL1922224)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human AKT1 using GSK3 (amino acids 14 to 27) as substrate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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