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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Dimer of Gag-Pol polyprotein [501-599]
(Human immunodeficiency virus type 1)
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
Ki: 900nM ΔG°: -34.3kJ/mole
pH: 5.5 T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Pepsin A
(Porcine)
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
Ki: 4.80E+3nM ΔG°: -30.4kJ/mole
T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasmepsin II
(Plasmodium falciparum)
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
Ki: 6.80E+3nM ΔG°: -29.3kJ/mole
pH: 4.5 T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasmepsin IV
(Plasmodium falciparum)
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
Ki: 5.60E+4nM ΔG°: -24.3kJ/mole
T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1 [22-457]
(Homo sapiens (Human))
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
IC50: >2.50E+5nM
T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Renin
(Homo sapiens (Human))
Philipps University Marburg
Ligand
BDBM32391
(iso-butyl-substituted sulfonamide, 9b)
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Affinity Data
IC50: >2.50E+5nM
T: 2°C
Assay Description:
Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI