Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/mole IC50:  3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataIC50:  0.740nMAssay Description:Displacement of [3H]CGP 12177 from human recombinant beta2 adrenergic receptor expressed in CHO cells measured after 120 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataKd:  182nMAssay Description:Displacement of [3H](-)CGP12177 from human beta1-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataKd:  0.245nMAssay Description:Displacement of [3H](-)CGP12177 from human beta2-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed