Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323443(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophenyl)...)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323443(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophenyl)...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at human melanocortin 4 receptor expressed in CHO cells assessed as cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323443(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophenyl)...)
Affinity DataEC50:  295nMAssay Description:Inhibition of human melatonin receptor type 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed