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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: 10.5nM
Assay Description:
Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Transporter
(Rattus norvegicus)
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: 290nM
Assay Description:
Displacement of [3H]nisoxetine from NET in rat cortical membranes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: 721nM
Assay Description:
Displacement of [3H]raclopride from dopamine D2 receptor in rat striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H1 receptor
(RAT)
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: >1.00E+3nM
Assay Description:
Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membranes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: 1.34E+3nM
Assay Description:
Displacement of [3H]paroxatine from SET in rat cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]DAMGO from mu opiate receptor in rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50202924
((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]DPDPE from delta opiate receptor in rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI