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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  10.5nMAssay Description:Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  290nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  721nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  1.34E+3nMAssay Description:Displacement of [3H]paroxatine from SET in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opiate receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202924((+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opiate receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed