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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50153838
(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
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Affinity Data
IC50: 166nM
Assay Description:
Inhibition of p38alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50153838
(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
Concentration required to inhibit human mitogen activated protein kinase p38 activity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Smoothened homolog
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50153838
(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI