Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311416(CHEMBL1078208 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetMotilin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311416(CHEMBL1078208 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)Copy SMILESCopy InChI

Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311416(CHEMBL1078208 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)Copy SMILESCopy InChI

Affinity DataEC50:  158nMAssay Description:Agonist activity at human gherlin receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI