Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL

LigandBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)Copy SMILESCopy InChI

Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL

LigandBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)Copy SMILESCopy InChI

Affinity DataKi:  47nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL

LigandBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)Copy SMILESCopy InChI

Affinity DataKi:  615nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI