Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM105075(CHEMBL2152708 | US8569281, 59)Copy SMILESCopy InChI

Affinity DataKi:  2.40nMAssay Description:Binding affinity to LRRK2More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM105075(CHEMBL2152708 | US8569281, 59)Copy SMILESCopy InChI

Affinity DataKi:  2.40nMAssay Description:Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM105075(CHEMBL2152708 | US8569281, 59)Copy SMILESCopy InChI

Affinity DataKi:  2.40nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI