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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM336564
(N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6- | US...)
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Affinity Data
IC50: 1.04E+4nM
Assay Description:
Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Di...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Isoform D of Beta-secretase 1 (BACE-I-432)
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM223427
(US9315520, 70)
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Affinity Data
IC50: 1.04E+4nM
pH: 4.5 T: 2°C
Assay Description:
The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI