Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113039((2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-ben...)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113039((2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-ben...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI