Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research

Curated by ChEMBL

LigandBDBM50042612(CHEMBL121610 | Sodium; 7-[5-(4-fluoro-2-methyl-phe...)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL

LigandBDBM50160796((E)-(3R,5S)-7-[5-(4-Fluoro-2-methyl-phenyl)-4-(4-f...)Copy SMILESCopy InChI

Affinity DataIC50:  8.40nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoChEBI
KEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI