Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306024(2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phen...)
Affinity DataIC50:  89nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306024(2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306024(2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phen...)
Affinity DataEC50:  3.24E+3nMAssay Description:Agonist activity at human Gal4-LBD fused LXRalpha LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306024(2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phen...)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at human Gal4-LBD fused LXRbeta LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed