Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBile acid receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM30331(Naphthoic acid-based analog, 1d)
Affinity DataEC50:  500nMAssay Description:The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM30331(Naphthoic acid-based analog, 1d)
Affinity DataEC50:  420nMpH: 7.5 T: 2°CAssay Description:The assay measures ligand-mediated interaction of the SRC-1 peptide with the FXR ligand binding domain, using biotinylated FXR LBD coupled to allophy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed