Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50355014(CHEMBL1834966)Copy SMILESCopy InChI

Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human FXR LBD transfected in african green monkey CV1 cells after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50355014(CHEMBL1834966)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human amino-terminal polyhistidine-tagged FXR alpha LBD (amino acids 237 to 472) assessed as cofactor peptide SRC-1 interaction w...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI