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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Muscarinic acetylcholine receptor M1
(RAT)
University Of Arkansas
Curated by
PDSP K
i
Database
Ligand
BDBM86047
(CAS_10595 | Lithocholyltaurine | NSC_10595)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
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Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
University Of Arkansas
Curated by
PDSP K
i
Database
Ligand
BDBM86047
(CAS_10595 | Lithocholyltaurine | NSC_10595)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Muscarinic acetylcholine receptor M3
(RAT)
University Of Arkansas
Curated by
PDSP K
i
Database
Ligand
BDBM86047
(CAS_10595 | Lithocholyltaurine | NSC_10595)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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KEGG
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PC sid
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Article
PubMed
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Target
Vitamin D3 receptor
(Homo sapiens (Human))
University Of Wisconsin
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
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Affinity Data
IC50: 1.45E+4nM
Assay Description:
Antagonist activity against VDR-LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of VDR agonist LG190178-induced SRC2-3 coac...
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Target Info
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
The Netherlands Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50420224
(CHEMBL2074694)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cells
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Target
Vitamin D3 receptor
(Homo sapiens (Human))
University Of Wisconsin
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Agonist activity at VP16 tagged-VDR-LBD (unknown origin) expressed in HEK293T cells assessed as SRC1 coactivator peptide recruitment after 16 hrs by ...
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Target Info
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Target
Ephrin type-A receptor 2
(Mus musculus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
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Affinity Data
IC50: 7.20E+4nM
Assay Description:
Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ...
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Target
Bile salt export pump
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50420224
(CHEMBL2074694)
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Affinity Data
IC50: 1.89E+5nM
Assay Description:
TP_TRANSPORTER: increase in dihydrofluorescein intracellular accumulation (dihydrofluorescein: 1 uM) in SK-E2 cells (expressing BSEP)
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Target Info
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Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
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Affinity Data
EC50: 847nM
Assay Description:
Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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ChEBI
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Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
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Affinity Data
EC50: 330nM
Assay Description:
Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation in presence of 3-isobutyl-1-methylxanthin...
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Target Info
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KEGG
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ChEBI
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Article
PubMed
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Target
Vitamin D3 receptor
(Homo sapiens (Human))
University Of Wisconsin
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.50E+5nM
Assay Description:
Agonist activity at VDR-LBD (unknown origin) expressed in Escherichia coli assessed as SRC2-3 coactivator peptide recruitment after 30 mins by fluore...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.01E+3nM
Assay Description:
Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vitamin D3 receptor
(Homo sapiens (Human))
University Of Wisconsin
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.50E+5nM
Assay Description:
Agonist activity at VDR-LBD (unknown origin) expressed in Escherichia coli assessed as SRC2-3 coactivator peptide recruitment after 30 mins by fluore...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50375593
(CHEMBL408701)
Copy SMILES
Copy InChI
Affinity Data
EC50: 290nM
Assay Description:
Agonist activity at human TGR5 expressed in CHO cells by luciferase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI