Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  64nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human MRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to mineralocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50:  570nMAssay Description:Displacement of TAMRA-labeled mifepristone from progesterone receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198973(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Affinity DataIC50: >2.00E+3nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed