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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
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Affinity Data
IC50: 64nM
Assay Description:
Inhibition of human GR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Glucocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64nM
Assay Description:
Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
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Copy InChI
Affinity Data
IC50: 130nM
Assay Description:
Inhibition of human MR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 130nM
Assay Description:
Binding affinity to mineralocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 570nM
Assay Description:
Inhibition of human PR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 570nM
Assay Description:
Displacement of TAMRA-labeled mifepristone from progesterone receptor (unknown origin) by fluorescence polarization competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50198973
(CHEMBL396029 | N-(1-(1H-indol-3-yl)propan-2-yl)-2,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+3nM
Assay Description:
Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 24 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI