Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 23 hits in this display
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
Ki: 0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...More data for this Ligand-Target Pair
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Ki: 0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 uL. CHO cell me...More data for this Ligand-Target Pair
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Ki: 0.100nM ΔG°: -59.4kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Ki: 0.100nM ΔG°: -59.4kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
Ki: 0.100nMAssay Description:compounds were performed with [3H]NMS at 1 nM and eleven different test compound concentrations. The test compounds were initially dissolved to a con...More data for this Ligand-Target Pair
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
Ki: 0.300nM ΔG°: -56.5kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
Ki: 0.300nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 uL. CHO cell me...More data for this Ligand-Target Pair
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
Ki: 0.300nMAssay Description:compounds were performed with [3H]NMS at 1 nM and eleven different test compound concentrations. The test compounds were initially dissolved to a con...More data for this Ligand-Target Pair
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
Ki: 0.300nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...More data for this Ligand-Target Pair
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
EC50: 1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
BDBM103779(US8551978, I-49 | US8816088, I-49 | US9394275, I-4...)
EC50: 1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
EC50: 1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
BDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
EC50: 1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
BDBM103778(US8551978, I-48 | US8816088, I-48 | US9394275, I-4...)
EC50: 1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair