Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 51 hits in this display
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Ki: 2.19E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Ki: 2.29E+3nMAssay Description:Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using...More data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Ki: 1.30E+4nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
IC50: 266nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
IC50: 900nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
EC50: 100nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
EC50: 310nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
EC50: 160nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
EC50: 1.35E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
EC50: 1.17E+4nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)
EC50: 6.57E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
EC50: 2.48E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
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