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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCollagenase ColG(Clostridium histolyticum)
Universita Degli Studi Di Firenze

LigandPNGBDBM11841(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
Affinity DataKi:  1.40E+4nMAssay Description:The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11841(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
Affinity DataKi:  1.70E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11841(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
Affinity DataKi:  1.80E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11841(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
Affinity DataKi:  1.90E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11841(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
Affinity DataKi:  2.10E+4nM ΔG°:  -26.4kJ/molepH: 6.0 T: 2°CAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed