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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Collagenase ColG
(Clostridium histolyticum)
Universita Degli Studi Di Firenze
Ligand
BDBM11841
(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
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Affinity Data
Ki: 1.40E+4nM
Assay Description:
The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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B.MOAD
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Ligand Info
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PC sid
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM11841
(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
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Affinity Data
Ki: 1.70E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM11841
(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
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Affinity Data
Ki: 1.80E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM11841
(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
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Affinity Data
Ki: 1.90E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM11841
(2-[(4-iodobenzene)sulfonamido]-3-phenyl-N-{1-[(5-s...)
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Affinity Data
Ki: 2.10E+4nM ΔG°: -26.4kJ/mole
pH: 6.0 T: 2°C
Assay Description:
Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI