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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
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Affinity Data
Ki: 1.22E+3nM
Assay Description:
Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.74E+3nM
Assay Description:
Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.60E+3nM
Assay Description:
Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Antagonist activity at human alpha4beta2 nAChR receptor expressed in human SH-SY5Y cells assessed as inhibition of carbamylcholine-induced 86Rb+ effl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >100nM
Assay Description:
Inhibition of [3H]serotonin uptake at human SERT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 473nM
Assay Description:
Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 950nM
Assay Description:
Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.62E+3nM
Assay Description:
Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.81E+3nM
Assay Description:
Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50302922
(1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.25E+3nM
Assay Description:
Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI