Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
121
hits in this display
Target
Histamine H1 receptor
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 29nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 173nM
Assay Description:
DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 372nM
Assay Description:
Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 441nM
Assay Description:
Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 520nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 560nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 562nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 570nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 600nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 648nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 784nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 871nM
Assay Description:
Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 937nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 940nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 950nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.50E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.80E+3nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.17E+3nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.64E+3nM
Assay Description:
NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
DrugBank
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.20E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.97E+3nM
Assay Description:
Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.10E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M5
(Homo sapiens (Human))
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Nicotinic acetylcholine receptor
(RAT)
University Of Kentucky
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nicotinic acetylcholine receptor
(RAT)
University Of Kentucky
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.33E+4nM
Assay Description:
SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Antagonist activity at human alpha4beta2 nAChR receptor expressed in human SH-SY5Y cells assessed as inhibition of carbamylcholine-induced 86Rb+ effl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >100nM
Assay Description:
Inhibition of [3H]serotonin uptake at human SERT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607015
(CHEMBL5220856)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607017
(CHEMBL5219762)
Copy SMILES
Copy InChI
Affinity Data
IC50: 430nM
Assay Description:
Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 443nM
Assay Description:
Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
Inhibition of DAT (unknown origin) assessed as transporter-mediated dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 658nM
Assay Description:
Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 658nM
Assay Description:
Inhibition of human DAT expressed in HEK293 cells assessed as inhibition of [3H]DA reuptake after 10 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 660nM
Assay Description:
Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 945nM
Assay Description:
Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607017
(CHEMBL5219762)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-2
(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of [3H]-5-dopamine reuptake in human DAT expressed in HEK293 cells by microbeta liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of human DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptake by micro beta scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of [3H]-5-dopamine reuptake in human DAT expressed in HEK293 cells by liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.23E+3nM
Assay Description:
Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.45E+3nM
Assay Description:
Inhibition of Norepinephrine (NA) reuptake using cloned human transporter was determined
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.57E+3nM
Assay Description:
Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human))
Barrow Neurological Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+3nM
Assay Description:
Antagonist activity at alpha3beta4 nicotinic receptor in human SH-SY5Y cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx a...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.85E+3nM
Assay Description:
Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.85E+3nM
Assay Description:
Inhibition of human NET expressed in HEK293 cells assessed as inhibition of [3H]NE reuptake after 10 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.85E+3nM
Assay Description:
Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607015
(CHEMBL5220856)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+3nM
Assay Description:
Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607014
(CHEMBL5219205)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70E+3nM
Assay Description:
Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+3nM
Assay Description:
Inhibition of dopamine (DA) reuptake using cloned human dopamine transporter was determined
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607014
(CHEMBL5219205)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10E+3nM
Assay Description:
Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607016
(CHEMBL5220410)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.24E+3nM
Assay Description:
Inhibition of human NET expressed in HEK293 cells assessed as reduction in [3H]-NE uptake by micro beta scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.24E+3nM
Assay Description:
Inhibition of [3H]-5-norepinephrine reuptake in human NET expressed in HEK293 cells by liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.24E+3nM
Assay Description:
Inhibition of [3H]-5-norepinephrine reuptake in human NET expressed in HEK293 cells by microbeta liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.24E+3nM
Assay Description:
Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50607016
(CHEMBL5220410)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.80E+3nM
Assay Description:
Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90E+3nM
Assay Description:
Non-competitive antagonist activity at alpha7 nAChR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholine receptor subunit alpha/beta/delta/gamma
(Homo sapiens (Human))
Barrow Neurological Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90E+3nM
Assay Description:
Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-4
(Homo sapiens (Human))
Barrow Neurological Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Antagonist activity at alpha4beta4 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Antagonist activity against human alpha4beta2 nAChR in SHEP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ efflux
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Antagonist activity at alpha4beta2 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70E+4nM
Assay Description:
Inhibition of [3H]paroxetine binding at serotonin transporter was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Mayo Foundation
US Patent
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90E+4nM
Assay Description:
HERG: The pre- and post-compound hERG current was evoked by a single voltage pulse consisting of a 20 s period holding at −70 mV, a 160 ms step...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
UDP-glucuronosyltransferase 2B10
(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.80E+4nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells after 90 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human SERTexpressed in HEK293 cells assessed as inhibition of [3H]5HT reuptake after 10 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1A4
(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.52E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1-6
(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1A1
(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 2B7
(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50048392
(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Displayed 1 to 50 (of 121 total ) |
Next
|
Last
>>