Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against rabbit lung indole N-methyl-transferase by using S-adenosyl-L-[methyl-3H]-methionine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung high-affinity cGMP phosphodiesterases (0.5-2 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028191((R)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung high-affinity cGMP phosphodiesterases (0.5-2 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung high-affinity cGMP phosphodiesterases (0.5-2 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028191((R)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung low-affinity cGMP phosphodiesterases (10-50 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028190(7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung low-affinity cGMP phosphodiesterases (10-50 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  7.00E+5nMAssay Description:Inhibition of human lung low-affinity cGMP phosphodiesterases (10-50 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028191((R)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibitory activity against rabbit lung indole N-methyl-transferase by using S-adenosyl-L-[methyl-3H]-methionine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibitory activity against catechol O-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed