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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Tyrosine-protein kinase ABL1 [1-999,Q252H]
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM68218
(Type II inhibitor, 12)
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Affinity Data
IC50: 19.6nM
pH: 7.5
Assay Description:
An in vitro kinase assay using phosphorylated recombinant human Abl kinase domains to phosphorylate a peptide substrate.
More data for this Ligand-Target Pair
Target Info
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MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase ABL1 [1-999,Q252H]
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM68218
(Type II inhibitor, 12)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27.2nM
pH: 7.5
Assay Description:
An in vitro kinase assay using dephophorylated conformationally inactive Abl kinase was obtained by treating pure recombinant Abl with Yersinia ester...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI