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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Lysophosphatidic acid receptor 3
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Affinity Data
Ki: 148nM
Assay Description:
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Copy InChI
Affinity Data
Ki: 425nM
Assay Description:
Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cells
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Affinity Data
IC50: 46nM
Assay Description:
Antagonist activity at LPA1 expressed in human chem1 cells assessed as effect on intracellular calcium mobilization by FLIPR assay
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Target
Lysophosphatidic acid receptor 1
(Rattus norvegicus)
Ajinomoto
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Affinity Data
IC50: 160nM
Assay Description:
Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Antagonist activity at LPA1 in human lung fibroblasts assessed as inhibition of LPA-induced contraction after 18 hrs by 3D collagen gel contraction a...
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Target
Lysophosphatidic acid receptor 3
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 301nM
Assay Description:
Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor
More data for this Ligand-Target Pair
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 510nM
Assay Description:
Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 762nM
Assay Description:
Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 800nM
Assay Description:
Antagonist activity at LPA1 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization measured after 120 ...
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidic acid receptor 2
(Homo sapiens)
Universidad Complutense De Madrid
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Affinity Data
IC50: 1.20E+3nM
Assay Description:
Antagonist activity at LPA2 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization measured after 120 ...
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Target
Lysophosphatidic acid receptor 3
(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+3nM
Assay Description:
Antagonist activity at LPA3 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization measured after 120 ...
More data for this Ligand-Target Pair
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Target
Lysophosphatidic acid receptor 5
(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by
ChEMBL
Ligand
BDBM50170859
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Antagonist activity at LPA5 receptor in human isolated platelets assessed as inhibition of hexadecyl-LPA-induced platelet aggregation after 3 mins
More data for this Ligand-Target Pair
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