Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)Copy SMILESCopy InChI

Affinity DataIC50:  72nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)Copy SMILESCopy InChI

Affinity DataIC50:  318nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI