Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50:  520nMAssay Description:Antagonist activity at progesterone receptor by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50:  1.51E+3nMAssay Description:Antagonist activity at glucocorticoid receptor by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed