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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Nicotinic acetylcholine receptor alpha9/alpha10
(RAT)
Hainan University
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
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Affinity Data
IC50: 19nM
Assay Description:
Antagonist activity at Sprague-Dawley rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Nicotinic acetylcholine receptor alpha9/alpha10
(RAT)
Hainan University
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
Copy SMILES
Copy InChI
Affinity Data
IC50: 109nM
Assay Description:
Inhibition of rat alpha9alpha10 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3
(Rattus norvegicus)
Hainan University
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
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Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Antagonist activity at Sprague-Dawley rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4
(Rattus norvegicus (Rat))
Hainan University
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
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Copy InChI
Affinity Data
IC50: 980nM
Assay Description:
Antagonist activity at Sprague-Dawley rat alpha6/alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by volt...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor; alpha9/alpha10
(Homo sapiens (Human))
Ocean University Of China
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
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Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor; alpha9/alpha10
(Homo sapiens (Human))
Ocean University Of China
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Rattus norvegicus (Rat))
Hainan University
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20E+3nM
Assay Description:
Antagonist activity at Sprague-Dawley rat alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage cla...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Ocean University Of China
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
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Copy InChI
Affinity Data
IC50: 7.10E+3nM
Assay Description:
Inhibition of rat alpha7 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Ocean University Of China
Curated by
ChEMBL
Ligand
BDBM50445324
(CHEMBL3104237)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp ass...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI