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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity to human EAAT1 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataKi:  3.80E+4nMAssay Description:Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed