Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Excitatory amino acid transporter 2
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40E+4nM
Assay Description:
Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Excitatory amino acid transporter 1
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.30E+4nM
Assay Description:
Binding affinity to human EAAT1 expressed in HEK293 cells in FMP (FLPR) assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Excitatory amino acid transporter 3
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.80E+4nM
Assay Description:
Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as inhibition of forskolin stimulated cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonist activity at rat mGlu1 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI