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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Cathepsin E
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
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Affinity Data
IC50: 0.354nM
Assay Description:
Inhibition of cathepsin E
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin E
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
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Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin D
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
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Affinity Data
IC50: 7.30nM
Assay Description:
Inhibition of human liver cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate pretreated for 15 mins followed b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
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Affinity Data
IC50: 2.23E+3nM
Assay Description:
Inhibition of TACE after 10 to 15 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Disintegrin and metalloproteinase domain-containing protein 9
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
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Affinity Data
IC50: 8.55E+4nM
Assay Description:
Inhibition of ADAM9 after 10 to 15 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 10
(Homo sapiens (Human))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50302109
(CHEMBL568553 | Grassystatin B)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.72E+4nM
Assay Description:
Inhibition of ADAM10 after 10 to 15 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI