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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-OT from binding to oxytocin receptor of rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  55nMAssay Description:Inhibition of radioligand [3H]-oxytocin binding at the oxytocin (OT) receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of [3H]AVP from binding to arginine vasopressin 1a (V1a) column of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  5.10E+3nMAssay Description:Displacement of [3H]-AVP from binding to Vasopressin receptor V2 of rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed