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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM144951
(US8952157, 133 | US9303025, 133)
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Copy InChI
Affinity Data
Ki: 0.0550nM ΔG°: -58.6kJ/mole
T: 2°C
Assay Description:
Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM144951
(US8952157, 133 | US9303025, 133)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0550nM ΔG°: -58.6kJ/mole
T: 2°C
Assay Description:
Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI