Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM189650(US10213433, Compound 217 | US11369599, Compound 21...)
BDBM189788(US10213433, Compound 361 | US11369599, Compound 36...)
Ki: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
BDBM189650(US10213433, Compound 217 | US11369599, Compound 21...)
BDBM189788(US10213433, Compound 361 | US11369599, Compound 36...)
BDBM189650(US10213433, Compound 217 | US11369599, Compound 21...)
BDBM189788(US10213433, Compound 361 | US11369599, Compound 36...)
Ki: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
BDBM189650(US10213433, Compound 217 | US11369599, Compound 21...)
BDBM189788(US10213433, Compound 361 | US11369599, Compound 36...)