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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM50231755
(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
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Affinity Data
Ki: 51nM
Assay Description:
Displacement of [3H]MPEP from rat mGluR5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Brain Science Institute
Curated by
ChEMBL
Ligand
BDBM50231755
(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Modulation of mGluR5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM50231755
(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Displacement of [3H]MPEP from rat mGluR5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Brain Science Institute
Curated by
ChEMBL
Ligand
BDBM50231755
(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI