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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Androgen receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50317659
(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
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Affinity Data
IC50: 110nM
Assay Description:
Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 days
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50317659
(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+3nM
Assay Description:
Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50317659
(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 days
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI