Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMineralocorticoid receptor(RAT)
Pfizer

Curated by ChEMBL

LigandBDBM50398062(CHEMBL2181930)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor after 18 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMineralocorticoid receptor(RAT)
Pfizer

Curated by ChEMBL

LigandBDBM50398062(CHEMBL2181930)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat kidney cytosolic fraction measured after 18 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50398062(CHEMBL2181930)Copy SMILESCopy InChI

Affinity DataIC50:  130nMAssay Description:Antagonist activity at mineralocorticoid receptor expressed in african green monkey COS7 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI