Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMineralocorticoid receptor(RAT)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlucocorticoid receptor(RAT)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataKi:  8.42E+4nMAssay Description:Displacement of [3H]-dexamethasone from rat glucocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50:  256nMAssay Description:Antagonist activity at human wild-type mineralocorticoid receptor expressed in CHO-K1 cells assessed as inhibition of aldosterone-induced transcripti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50:  276nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMineralocorticoid receptor(RAT)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50: <500nMAssay Description:Binding affinity to rat mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-methyltrienolene from human androgen receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-dexamethasone from recombinant full length human glucocorticoid receptor expressed in baculovirus infected insect cells incubate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50004519(CHEMBL2181929)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-estradiol from recombinant full-length human estrogen beta receptor expressed in baculovirus infected insect cells incubated ove...More data for this Ligand-Target Pair
In DepthDetails PubMed