Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Pfizer

Curated by ChEMBL

LigandBDBM50009839(2-Methyl-1,4-dioxo-1,2,3,4-tetrahydro-naphthalene-...)Copy SMILESCopy InChI

Affinity DataIC50:  8.20E+4nMAssay Description:Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrateChecked by AuthorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseChEBI
KEGGPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAldo-keto reductase family 1 member A1(Sus scrofa)
Pfizer

Curated by ChEMBL

LigandBDBM50009839(2-Methyl-1,4-dioxo-1,2,3,4-tetrahydro-naphthalene-...)Copy SMILESCopy InChI

Affinity DataIC50:  4.90E+5nMAssay Description:Selectivity ratio measured as the IC50 ratio of aldehyde/aldose reductase valuesChecked by AuthorMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseChEBI
KEGGPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI