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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197673
(CHEMBL3922315)
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Affinity Data
IC50: 32nM
Assay Description:
Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate addition
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197666
(CHEMBL3977401)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate addition
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197673
(CHEMBL3922315)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197666
(CHEMBL3977401)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197667
(CHEMBL3968927)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197667
(CHEMBL3968927)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+3nM
Assay Description:
Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate addition
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50197673
(CHEMBL3922315)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin) expressed in Escherichia coli co-expressing human NADPH reductase using both 7-benzyloxyquinolone and diethoxyf...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI