Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50078017(CHEMBL3417397)Copy SMILESCopy InChI

Affinity DataKi:  1.60E+3nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBcl-2-like protein 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50078017(CHEMBL3417397)Copy SMILESCopy InChI

Affinity DataKi:  3.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50078017(CHEMBL3417397)Copy SMILESCopy InChI

Affinity DataKi:  1.29E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI