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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50128110
(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
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Affinity Data
Ki: 0.860nM
Assay Description:
Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Universit£
Curated by
ChEMBL
Ligand
BDBM50128110
(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
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Affinity Data
Ki: 0.860nM
Assay Description:
Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Cavia porcellus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50128110
(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
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Affinity Data
Ki: 3.70nM
Assay Description:
Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sigma intracellular receptor 2
(Rattus norvegicus (Rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50128110
(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
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Affinity Data
Ki: 239nM
Assay Description:
Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI