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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
National Medicines Institute
Curated by
ChEMBL
Ligand
BDBM25871
(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
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Affinity Data
Ki: 37nM
Assay Description:
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
National Medicines Institute
Ligand
BDBM25871
(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
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Affinity Data
IC50: 50nM
pH: 7.7 T: 2°C
Assay Description:
Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
National Medicines Institute
Curated by
ChEMBL
Ligand
BDBM25871
(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
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Affinity Data
IC50: 50nM
Assay Description:
Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI