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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053468
(4-Hydroxy-5-methyl-1-m-tolyl-[1,2,4]triazinan-3-on...)
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Affinity Data
IC50: 4.80E+3nM
Assay Description:
In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053468
(4-Hydroxy-5-methyl-1-m-tolyl-[1,2,4]triazinan-3-on...)
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Copy InChI
Affinity Data
IC50: 8.40E+3nM
Assay Description:
Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI