Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

LigandBDBM50376112(CHEMBL258845)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 8(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL

LigandBDBM50376112(CHEMBL258845)Copy SMILESCopy InChI

Affinity DataIC50:  670nMAssay Description:Inhibition of JNK1 in rat H9c2 cells assessed as inhibition of anisomycin-induced cJun phosphorylation after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI