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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Peptidyl-prolyl cis-trans isomerase FKBP5
(Homo sapiens (Human))
Max Institute Of Psychiatry
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
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Affinity Data
Ki: 2.70E+3nM
Assay Description:
Binding affinity to human FKBP51 by competitive fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human))
Ariad Gene Therapeutics
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
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Affinity Data
IC50: 44nM
Assay Description:
Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human))
Ariad Gene Therapeutics
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 114nM
Assay Description:
Binding affinity to FKBP12 by competitive fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human))
Ariad Gene Therapeutics
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
Binding affinity to FKBP12 by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP5
(Homo sapiens (Human))
Max Institute Of Psychiatry
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+3nM
Assay Description:
Binding affinity to FKBP51 FK1 domain by competitive fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP5
(Homo sapiens (Human))
Max Institute Of Psychiatry
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.36E+3nM
Assay Description:
Binding affinity to FKBP51 FK1 domain by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP4
(Homo sapiens (Human))
Max Planck Institute Of Psychiatry
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.37E+3nM
Assay Description:
Binding affinity to FKBP52 FK1 domain by competitive fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Peptidyl-prolyl cis-trans isomerase FKBP4
(Homo sapiens (Human))
Max Planck Institute Of Psychiatry
Curated by
ChEMBL
Ligand
BDBM50132556
((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.05E+4nM
Assay Description:
Binding affinity to FKBP52 FK1 domain by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI