Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hits in this display   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL

LigandBDBM50229700(CHEMBL4085167)Copy SMILESCopy InChI

Affinity DataEC50:  12nMAssay Description:Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProtUniProtKB/TrEMBL
antibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI