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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of RIP1 (unknown origin) using MBP as substrate preincubated for 15 mins followed by MBP/ATP mixture addition measured after 90 mins by AD...
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
Copy SMILES
Copy InChI
Affinity Data
IC50: 298nM
Assay Description:
Inhibition of human RIPK1 incubated for 40 min in presence of ATP by ADP-Glo luminescence kinase assay
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: >3.50E+3nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
Copy SMILES
Copy InChI
Affinity Data
EC50: 28nM
Assay Description:
Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Mus musculus)
National Institute Of Biological Sciences
Curated by
ChEMBL
Ligand
BDBM50229025
(CHEMBL4092421)
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Affinity Data
EC50: 27nM
Assay Description:
Inhibition of RIP1 in mouse L929 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 6 hrs by Cell Titer-Glo luminescent cell vi...
More data for this Ligand-Target Pair
Target Info
PDB
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CHEMBL
PC cid
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