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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
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Target
Beta-secretase 1
(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by
ChEMBL
Ligand
BDBM50357482
(CHEMBL1917916)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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